Paolo De Giosa primarily uses painting, on unusual media such as old newspapers, blending his training in industrial design and graphic design with deep humanistic and philosophical roots. His refined technique and figurative expressionist style translate intense gazes and melancholic introspection into images, often inspired by literature. In his works, he explores inner restlessness and emotional absence, conveying a sense of vivid depth through the disfigurement or absence of anatomical features, conveying poignant and compelling emotions. "Le Assenze" (The Absences) is the title of a pictorial research he began in 2012 and continues today, depicting women's faces with anatomical disfigurement or missing parts. In 2017, in a solo exhibition titled "NOVECENTO," De Giosa exhibited 26 works from this research at the Basilio Cascella Museum in Pescara for a month-long solo exhibition.